A. Tamrakar, S. Chen, R. Ramachandran. A DEM model based study to quantitatively compare the effect of wet and dry binder addition in high shear wet granulation processes. : Chemical Engineering Research and Design (Accepted Dec. 2018)
W. Meng, K. S. Rao, R.D. Snee, R. Ramachandran, F. Muzzio. A comprehensive analysis and optimization of continuous twin-screw granulation processes via sequential experimentation strategy. International Journal of Pharmaceutics. 556, 349-362, February 2019.
T. Gao, A. Singaravelu, S. Oka, R. Ramachandran, F. Stepanek, N. Chawla, H.N. Emady. Granule Formation and Structure from Single Drop Impact on Heterogeneous Powder Beds. International Journal of Pharmaceutics. 552 (1-2), 56-66, December 2018
G. Pereira, S. Muddu, A. Roman, D. Clancy, B. Igne, C. Airiau, F. Muzzio, M. Ierapetritou, R. Ramachandran, R. SIngh. Combined Feedforward/Feedback Control of an Integrated Continuous Granulation Process. Journal of Pharmaceutical Innovation. October 2018
S. Muddu, A.Tamrakar, P. Pandey, R.Ramachandran. Model Development and Validation of Fluid Bed Wet Granulation with Dry Binder Addition using a Population Balance Model Methodology. Processes , 6(9), 154, 2018
C. Sampat, F.Bettencourt Y. Baranwal, I. Paraskevakos, A. Chaturbedi, S. Karkala, S. Jha, R. Ramachandran, M. Ierapetritou, A parallel unidirectional coupled DEM-PBM model for the efficient simulation of computationally intensive particulate process systems. Computers and Chemical Engineering, 119, 128-142, 2018
N. Metta, M. verstraten, M. Ghijs, A. Kumar, E. Schaefer, R. Singh, T. De Beer, I. Nopens, P. Cappyuns, I. Van Asche, M. Ierapetritou, R. Ramachandran. Model development and prediction of particle size distribution, density and friability of a comilling operation in a continuous pharmaceutical manufacturing process. International Journal of Pharmaceutics. 549(1-2), 271-282, October 2018
A.Chaturbedi, P. Pandey, D. Bindra, J.P. Reddy, B. Lang, D. Buckley, R. Ramachandran. Predictive population balance model development and validation of the effect of HSWG process parameters on granule properties, Powder Technology, 338, 391-401,2018
H.Cao, S.Mushnoori, B.Higgins, C.Kollipara, A.Fermier, D.Hausner, S.Jha, R.Singh, M.Ierapetritou and R.Ramachandran. A Systematic Framework for Data Management and Integration in a Continuous Pharmaceutical Manufacturing Processing Line. Process, 6(5), 53, 2018.
A.Kataria, S. Oka, D. Smrcka, Z. Grof, F. Stepanek, R. Ramachandran. " A quantitative analysis of drug migration during granule drying " Chemical Engineering Research and Design, 136, 199-206, 2018.